In some distant future, it\'s common knowledge that all wolves have been extinct for 200 years. However, it seems this fact is false.
Kiba, a lone wolf wanders into a city, trying to sniff out the Lunar Flowers that are suppose to lead whoever follows the scent to paradise. The source of the smell is Cheza, also known as the Flower Damsel, a girl who sleeps in what appears to be suspended animation in a lab. She and the wolves are drawn to each other, and Kiba hopes to find paradise once he finds the source of the scent of Lunar Flowers (which he soon finds out is Cheza).
However, once Kiba along with Hige finds Cheza, she is kidnapped by a mysterious person called Darcia, and Kiba\'s search begins anew.
Before he leaves the city, he meets 3 other wolves, Tsume, Hige and Toboe. All four wolves have very different personalities and ideas, and their friendliness towards each other is a little rough around the edges. However, they soon band together to continue to search for the Lunar Flowers, and hopefully be lead to paradise.