Saishu Heiki Kanojo (Saikano for short) focuses on the awkward romance between its main characters, Shuuji and Chise. She confesses feelings for him after being put up to the task by Shuji\'s friend, Akemi. For her, it\'s a new experience. For him, relationships are a pain, and expressing his feelings is difficult. As a result, he\'s extremely standoffish toward her - add in her timidness, and it seems like a recipe for failure. That is, until a remarkable thing happens: they decide to actually try for love. There\'s just one problem--Chise. Chise is cute...but slow. Tiny and timid, not to mention a klutz. Her grades are below average, but her World History is good for some reason, although she knows it won\'t benefit her much in life. She have a habit of saying \'I\'m sorry\', her goal in life is \'to become stronger\'. The irony is that such a girl would become the ultimate weapon, and become Japan\'s only reliable defense against the mysterious foreign threat. Chise becomes constantly torn between her humanity and her role as a mass weapon of destruction. Her love for Shuji quickly becomes the only shred of humanity that she can cling to.